Research will highlight the latest advancements in cardiovascular care through 55 abstract presentations
West Orange, N.J., March 28, 2025 – Physician-scientists from RWJBarnabas Health and Rutgers Health will showcase a comprehensive collection of innovative cardiovascular research at this year’s American College of Cardiology’s Annual Scientific Session & Expo (ACC.25), taking place in Chicago, IL from March 29-31, 2025. A total of 55 abstracts will be presented, featuring clinical data and analyses that advance the understanding, treatment, and prevention of cardiovascular disease.
Research presented at the conference was conducted by residents and faculty in the cardiovascular service at Community Medical Center, Cooperman Barnabas Medical Center, Jersey City Medical Center, Newark Beth Israel Medical Center and Robert Wood Johnson University Hospital. RWJBarnabas Health cardiac centers of excellence are nationally recognized for patient care and superior outcomes, including being named as one of Becker’s top 100 Great Heart Programs in the country and recognized by American College of Cardiology as a Proven Quality Program. Rutgers Health faculty presenting at the conference represents the Division of Cardiology and the Division of Cardiothoracic Surgery at Rutgers New Jersey Medical School, and the Division of Cardiovascular Diseases and Hypertension and the Division of Cardiothoracic Surgery at Robert Wood Johnson Medical School.
“We continue to drive advancements in cardiovascular care and enhance patient outcomes through transformative research and clinical excellence,” said Conor Barrett, MD, MBA, Senior Vice President and Chief Clinical Officer of RWJBarnabas Health Heart and Vascular Services. “The data we are presenting at ACC.25 underscores our ongoing commitment to innovation in the prevention, diagnosis, and treatment of heart and vascular diseases. By leveraging cutting-edge science and fostering collaboration with leading experts, we are developing strategies that not only reduce cardiovascular risk but also improve the overall quality of life for patients in our communities.”
RWJBarnabas Health and Rutgers Health remain at the forefront of cardiovascular innovation. Their participation at ACC.25 reinforces their ongoing commitment to advancing research, improving patient outcomes, and shaping the future of heart and vascular care.
Highlights of the accepted abstracts include the following presentations:
- Research exploring the use of machine learning models based on cardiac ultrasound radiomics (ultrasomics) to identify myocardial infarction with high accuracy. It compares traditional handcrafted ultrasound features with deep learning-based 3D convolutional neural networks, demonstrating that ultrasomics could provide the association with CMR-driven infarct localization and myocardial tissue characterization in acute myocardial infarction patients.
- Highlights from a Fragility Index Analysis of the ARIES-HM3 trial, which evaluated the robustness of findings supporting an aspirin-free regimen in HeartMate III LVAD patients. The analysis confirms that the composite primary outcome (survival free of a major nonsurgical hemocompatibility-related adverse events, including stroke, pump thrombosis, major bleeding, or arterial thrombosis) remains robust with an FI of 24, driven primarily by a reduction in bleeding events, reinforcing the trial’s potential practice-changing impact.
- Findings from the FINEARTS-HF trial which demonstrated efficacy of finerenone in the reduction of a composite endpoint of cardiovascular death and heart failure events in patients with left ventricular ejection fraction (LVEF) ≥40%. This fragility index analysis confirms that these findings are remarkably robust, with a Fragility Index (FI) of 112, primarily driven by a significant reduction in heart failure hospitalizations (F1 of 112), making it more robust than most practice-changing trials in the cardiology field.
- Immune checkpoint inhibitors (ICIs) are widely used in cancer treatment but can cause rare, life-threatening myocarditis. Our findings highlight that timely recognition and management of ICI-induced myocarditis are crucial to preventing severe cardiac complications.
- Hypertrophic obstructive cardiomyopathy (HOCM) is a complex, life-threatening disease with limited treatment options, however the approval of Mavacamten introduced a novel approach by directly targeting the disease’s molecular pathology. Our findings suggest the need for further research to evaluate long-term side effects of Mavacamten.
The full list of presentations at this year’s ACC.25 Annual Scientific Session & Expo follows:
Oral Presentations | |||
Abstract and Session No. | Title | Presentation Date/Time | Location |
HIGHLIGHTED ORIGINAL RESEARCH: VALVULAR DISEASES AND THE YEAR-IN-REVIEW | Monday, March 31 11:00 AM CT | S503B | |
TRENDS AND DISPARITIES IN CARDIOVASCULAR-RELATED MATERNAL MORTALITY IN THE UNITED STATES: 1999-2022 | Saturday, March 29 9:42 AM CT | Moderated Poster Theater 9 | |
ATYPICAL LEFT MAIN CORONARY ARTERY ORIGIN CAUSING MYOCARDIAL ISCHEMIA | Sunday, March 30 2:48 PM CT | Moderated Poster Theater 14 | |
HIDDEN IN THE HEART: A RARE PRIMARY CARDIAC NEUROENDOCRINE TUMOR | Sunday, March 30 3:42 PM CT | Moderated Poster Theater 14 | |
Poster Presentations | |||
(Board 141) | ASSESSMENT OF THE ETIOLOGY OF CIRRHOSIS AND MELD 3.0 SCORES ON PRESENCE AND SEVERITY OF DIASTOLIC DYSFUNCTION IN LIVER TRANSPLANT PATIENTS | Saturday, March 29 9:30 AM CT | South Hall |
(Board 170) | THE KIDNEYS STRIKE BACK: NEPHROTIC SYNDROME AND ACUTE MYOCARDIAL INFARCTION | Saturday, March 29 9:30 AM CT | South Hall |
(Board 187) | BALLOONS, HARMLESS TOY OR TREACHEROUS DEVICE: A CASE OF INTRA-AORTIC BALLOON PUMP RUPTURE | Saturday, March 29 9:30 AM CT | South Hall |
(Board 17) | PREVALENCE OF ABNORMAL ECG FINDINGS IN ADOLESCENT FEMALE ATHLETES: A CROSS-SECTIONAL STUDY | Saturday, March 29 11:00 AM CT | South Hall |
(Board 27) | SOCIAL DEPRIVATION INDEX AND CARDIOVASCULAR RISK FACTORS IN YOUTH CARDIAC SCREENINGS: ANALYSIS OF THE HEARTBYTES DATABASE | Saturday, March 29 11:00 AM CT | South Hall |
(Board 181) | ASPIRIN FREE WITH HEARTMATE III? HOW ROBUST ARE THE FINDINGS OF ARIES-HM3 | Saturday, March 29 11:00 AM CT | South Hall |
(Board 232) | FROM AN INDOLENT COURSE TO FULMINANT MYOCARDITIS: CARDIAC SARCOIDOSIS CAUSING REFRACTORY VENTRICULAR TACHYCARDIA | Saturday, March 29 11:00 AM CT | South Hall |
(Board 231) | DON’T BE RASH, ALWAYS CONSIDER BRASH SYNDROME | Saturday, March 29 11:00 AM CT | South Hall |
(Board 67) | LIVING IN SMALL RURAL APPALACHIAN COMMUNITIES IS ASSOCIATED WITH A HIGHER INCIDENCE OF NON-CALCIFIED PLAQUE ON CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY | Saturday, March 29 12:00 PM CT | South Hall |
(Board 105) | RACIAL DISPARITIES IN THE TRENDS, CLINICAL CHARACTERISTICS AND OUTCOMES OF PATIENTS UNDERGOING CORONARY ATHERECTOMY | Saturday, March 29 2:00 PM CT | South Hall |
(Board 153) | PULMONARY EMBOLISM AND RIGHT VENTRICULAR STRAIN AFTER UTERINE ARTERY MICROSPHERE EMBOLIZATION | Saturday, March 29 2:00 PM CT | South Hall |
(Board 43) | IMPACT OF RACIAL DISPARITIES ON CARDIOVASCULAR OUTCOMES IN PATIENTS UNDERGOING INTENSIVE CARDIAC REHABILITATION | Saturday, March 29 3:30 PM CT | South Hall |
(Board 51) | COMPARING IN-HOSPITAL OUTCOMES BETWEEN TAKOTSUBO CARDIOMYOPATHY PATIENTS IN SHOCK MANAGED MEDICALLY VERSUS THOSE MANAGED WITH MECHANICAL CIRCULATORY SUPPORT | Saturday, March 29 3:30 PM CT | South Hall |
(Board 146) | HOW ROBUST ARE THE FINDINGS OF THE FINEARTS-HF TRIAL: A FRAGILITY INDEX ANALYSIS | Saturday, March 29 3:30 PM CT | South Hall |
(Board 84) | SEX DISPARITIES IN ACUTE CORONARY SYNDROME AMONG YOUNG AND MIDDLE-AGED ADULTS: A EPIDEMIOLOGICAL META-ANALYSIS | Sunday, March 30 10:30 AM CT | South Hall |
(Board 192) | WHERE RADIATION ABUTS THE EGGSHELL, A RARE CASE OF CASEOUS MITRAL ANNULAR CALCIFICATION SPAWNING FROM RADIATION THERAPY | Sunday, March 30 10:30 AM CT | South Hall |
(Board 251) | FROM BLOODSTREAM TO PERICARDIUM: CANDIDA PARAPSILOSIS AS A RARE CULPRIT OF NEAR FATAL CARDIAC TAMPONADE | Sunday, March 30 10:30 AM CT | South Hall |
(Board 167) | TO REVERSE OR NOT TO REVERSE: MULTIPLE CONGENITAL DEFECTS LEADING TO EISENMENGER'S SYNDROME | Sunday, March 30 1:30 PM CT | South Hall |
(Board 169) | TAKOTSUBO CARDIOMYOPATHY INDUCED PERICARDITIS WITH LVOT OBSTRUCTION IN POSTMENOPAUSAL HYPERTHYROID FEMALE | Sunday, March 30 1:30 PM CT | South Hall |
(Board 194) | NOVEL APPROACH FOR TRICUSPID VALVE ENDOCARDITIS WITH PATENT FORAMEN OVALE: ANGIOVAC WITH SENTINEL CEREBRAL PROTECTION DEVICE TO REDUCE STROKE RISK FROM SEPTIC EMBOLI | Sunday, March 30 1:30 PM CT | South Hall |
(Board 183) | EFFECT OF SUBSTANCE USE DISORDER ON NEAR-TERM OUTCOMES OF TAKOTSUBO CARDIOMYOPATHY | Sunday, March 30 3:00 PM CT | South Hall |
(Board 237) | A RARE INSTANCE OF PULMONARY HYPERTENSION PREVENTING CARDIAC TAMPONADE IN A PATIENT WITH MYOPERICARDITIS ASSOCIATED WITH LARGE PERICARDIAL EFFUSION | Monday, March 31 10:30 AM CT | South Hall |
(Board 214) | PLUGGING THE LEAK: A CASE OF SUCCESSFUL PLUG CLOSURE OF PERFORATED ANTERIOR MITRAL VALVE LEAFLET WITH AMPLATZER OCCLUDER DEVICE | Sunday, March 30 3:00 PM CT | South Hall |
(Board 219) | CARDIAC FIBROMA: RARE TUMOR, COMPLEX DECISIONS | Sunday, March 30 3:00 PM CT | South Hall |
(Board 233) | RESISTANT VENTRICULAR ARRHYTHMIAS SUPPRESSED BY OVERDRIVE PACING IN HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY WITH COVID-19 | Sunday, March 30 3:00 PM CT | South Hall |
(Board 247) | APPROACH TO MANAGEMENT OF IMMUNE CHECKPOINT INHIBITOR-INDUCED VERSUS ACUTE VIRAL MYOCARDITIS | Sunday, March 30 3:00 PM CT | South Hall |
(Board 58) | CONTRASTING BASELINE HEMODYNAMIC SIGNATURES IN CARDIOGENIC SHOCK FROM ACUTE MYOCARDIAL INFARCTION AND ACUTE HEART FAILURE: A META ANALYSIS | Monday, March 31 9:00 AM CT | South Hall |
(Board 79) | A NEW MODEL FOR PREDICTION OF MYOCARDIAL INJURY OF NON-ELECTIVE SURGERY IN ELDERLY | Monday, March 31 9:00 AM CT | South Hall |
(Board 188) | VENTRICULAR FIBRILLATION-INDUCED STENT DISLODGEMENT: A NOVEL RETRIEVAL TECHNIQUE USING STENT BOOST IMAGING | Monday, March 31 9:00 AM CT | South Hall |
(Board 223) | A RARE CASE OF COMPLETE HEART BLOCK FROM COXSACKIE VIRUS | Monday, March 31 9:00 AM CT | South Hall |
(Board 259) POSTER | THROWN FOR A LOOP: LUPUS INDUCED HEART FAILURE IN THE SETTING OF ALCOHOL WITHDRAWAL | Monday, March 31 9:00 AM CT | South Hall |
(Board 181) | SEX-SPECIFIC DIFFERENCES IN HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH HEART FAILURE: A SYSTEMATIC REVIEW AND META-ANALYSIS | Monday, March 31 10:30 AM CT | South Hall |
(Board 195) | STEP-WISE MULTIMODALITY IMAGING TO DIAGNOSE A CARDIAC LIPOMA | Monday, March 31 10:30 AM CT | South Hall |
(Board 228) | SCN5A MUTATION IN PROGRESSIVE CARDIAC CONDUCTION DISEASE WITH URTICARIA PIGMENTOSA: A NOVEL CARDIAC-CUTANEOUS SYNDROME? | Monday, March 31 10:30 AM CT | South Hall |
(Board 222) | NIVOLUMAB AND IPILIMUMAB-INDUCED FATAL HIGH-DEGREE AV BLOCK, CARDIOGENIC SHOCK AND SUSPECTED MYOCARDITIS | Monday, March 31 10:30 AM CT | South Hall |
(Board 254) | ACUTE MYOPERICARDITIS AS A MANIFESTATION OF HYDROGEN SULFIDE POISONING | Monday, March 31 10:30 AM CT | South Hall |
(Board 168) | SNARE WITH NO SCARE: SUCCESSFUL PERCUTANEOUS RETRIEVAL OF RETAINED CORONARY DEVICES | Monday, March 31 12:00 PM CT | South Hall |
(Board 251) | WHEN A BAD LIVER LEADS TO A BROKEN HEART: A CASE OF TAKOTSUBO CARDIOMYOPATHY WITH TORSADES DE POINTES POST-ORTHOTOPIC LIVER TRANSPLANT | Monday, March 31 12:00 PM CT | South Hall |
(Board 252) | CARDIOGENIC SHOCK SECONDARY TO LUPUS FLARE IN A WOMAN ON HYDROXYCHLOROQUINE | Monday, March 31 12:00 PM CT | South Hall |
(Board 264) | BLURRING THE BOUNDARY BETWEEN CARDIO-OBSTETRICS AND CARDIO-ONCOLOGY: WHEN PRIOR CANCER PATIENTS BECOME PERIPARTUM PATIENTS | Monday, March 31 12:00 PM CT | South Hall |
(Board 123) | IMPACT OF CARDIAC IMPLANTABLE ELECTRICAL DEVICES ON THE OUTCOMES OF HOSPITALIZED PATIENTS WITH INFECTIVE ENDOCARDITIS: ANALYSIS OF THE NATIONAL INPATIENT SAMPLE DATABASE | Saturday, March 29 9:30 AM CT | South Hall |
Moderated Poster Presentations | |||
ANTERIOR MEDIASTINAL MYXOFIBROSARCOMA LEADING TO EXTERNAL CARDIAC COMPRESSION AND PERICARDIAL EFFUSION IN A YOUNG FEMALE | Saturday, March 29 3:42 PM CT | Moderated Poster Theater 13 | |
SEE-SAW IN THE HIS-PURKINJE SYSTEM: PEMBROLIZUMAB INDUCED MYOCARDITIS DISGUISED AS BIDIRECTIONAL VENTRICULAR TACHYCARDIA | Sunday, March 30 10:48 AM CT | Moderated Poster Theater 13 | |
ACC COMPLEX CLINICAL CASES: CORONARY, PERIPHERAL AND STRUCTURAL INTERVENTIONS (SESSION 2) | Sunday, March 30 11:30 AM CT | Moderated Poster Theater 15 | |
HANDCRAFTED VERSUS DEEP-LEARNING-BASED CARDIAC ULTRASOUND RADIOMICS FOR ACUTE MYOCARDIAL INFARCT TISSUE CHARACTERIZATION | Sunday, March 30 2:36 PM CT | Moderated Poster Theater 8 | |
ACC COMPLEX CLINICAL CASES: HEART FAILURE AND CARDIOMYOPATHIES (SESSION 2) MODERATOR: CHONYANG ALBERT | Sunday, March 30 2:00 PM CT | Moderated Poster Theater 15 | |
PERCUTANEOUS MECHANICAL ASPIRATION OF CATHETER ASSOCIATED THROMBUS/VEGETATIONS IN THE VENA CAVA: A CASE SERIES | Monday, March 31 9:48 AM CT | Moderated Poster Theater 4 | |
POMALIDOMIDE-INDUCED EOSINOPHILIC MYOCARDITIS: A CASE OF RARE CARDIOVASCULAR TOXICITY | Monday, March 31 10:12 AM CT | Moderated Poster Theater 14 | |
MAVACAMTEN INDUCED GENERALIZED SKELETAL MYOPATHY IN AN ELDERLY FEMALE: A NEW SIDE EFFECT | Monday, March 31 12:06 PM CT | Moderated Poster Theater 11 | |
Scientific and Education Session | |||
NORMAL STRESS ECHO OR MYOCARDIAL PERFUSION IMAGES WITH ABNORMAL STRESS ECG: WHAT NOW? | Saturday, March 29 3:53 PM CT | S403A | |
PUTTING THE IQ INTO ARTIFICIAL INTELLIGENCE FOR CARDIAC IMAGING | Sunday, March 30 1:30 PM CT | S402A | |
About RWJBarnabas Health
RWJBarnabas Health is the largest, most comprehensive academic health care system in New Jersey, with a service area covering eight counties with five million people. The system includes twelve acute care hospitals – Clara Maass Medical Center in Belleville, Community Medical Center in Toms River, Cooperman Barnabas Medical Center in Livingston, Jersey City Medical Center in Jersey City, Monmouth Medical Center in Long Branch, Monmouth Medical Center Southern Campus in Lakewood, Newark Beth Israel Medical Center in Newark, Robert Wood Johnson University Hospital in New Brunswick, Robert Wood Johnson University Hospital Somerset in Somerville, Robert Wood Johnson University Hospital Hamilton in Hamilton, Robert Wood Johnson University Hospital Rahway in Rahway and Trinitas Regional Medical Center in Elizabeth, three acute care children’s hospitals, Children’s Specialized Hospital with a network of outpatient pediatric rehabilitation centers, a freestanding 100-bed behavioral health center, two trauma centers, a satellite emergency department, ambulatory care centers, geriatric centers, the state’s largest behavioral health network, comprehensive home care and hospice programs, fitness and wellness centers, retail pharmacy services, affiliated medical groups, multi-site imaging centers and two accountable care organizations.
RWJBarnabas Health is among New Jersey’s largest private employers – with more than 41,000 employees and 9,000 physicians– and routinely captures national awards for outstanding quality and safety. RWJBarnabas Health launched an affiliation with Rutgers University to create New Jersey’s largest academic health care system. The collaboration aligns RWJBarnabas Health with Rutgers' education, research and clinical activities, including those at the Rutgers Cancer Institute of New Jersey - the state's only NCI-designated Comprehensive Cancer Center - and Rutgers University Behavioral Health Care.
For journalists – contact:
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