Dr. Louis Stein is a cardiothoracic surgeon who performs all forms of adult cardiac surgery and specific interests include Valvular Heart Disease and Heart Failure. The son of a surgeon, Dr. Stein is a native to the region. He received his undergraduate degree, Master’s of Health Science, and PhD from the Johns Hopkins University. He obtained his Doctor of Medicine from Jefferson Medical College in Philadelphia, PA and subsequently completed a residency in General Surgery at the Yale School of Medicine / Yale-New Haven Hospital. Dr. Stein went on tocomplete a Fellowship in Cardiothoracic Surgery at NYU Langone Medical Center. As a clinical instructor at Stanford University, he was trained in ECMO, Ventricu lar Assist Devices (VADs), and Heart and Lung Transplantation. Prior to joining RWJBarnabas Health, Dr. Stein was on the faculty at Albany Medical College, where he received the Grateful Patients and Families Champion Award.
Dr. Stein focuses on addressing the challenges of End Stage Heart and Lung Disease with ECMO, VADs, and Transplantation. He is the Surgical Director of the NBI ECMO and Temporary Mechanical Support Program. Dr. Stein also has a particular interest in the treatment Valvular Heart Disease with percutaneous techniques such as TAVR and minimally invasive surgical techniques. Dr. Stein is the Director of Cardiovascular Research for the Department, and is active in both clinical and laboratory investigations. He has authored over 30 peer reviewed papers, commentaries, and book chapters, serves as a reviewer for several journals, and is member of the editorial boards of the American Journal of Cardiology and the Journal of Thoracic and Cardiovascular Surgery.
Philosophy of Care:
It is vital to remember we are treating a unique patient – treatment decisions should be tailored to them as an individual. My job is to not only perform surgery, but to educate patients about their disease and treatment so they are comfortable with their plan of care. Each patient should be treated as though they were a member of the family.
Peer Reviewed Journals:
- Stein LH, Silvestry, SC, “ Invited Expert Opinion: Algorithmic management of postcardiotomy shock with mechanical support: Bring a map, a plan, and your parachute—and know how to use all three” JTCVS Open. 2021 https://doi.org/10.1016/j.xjon.2021.10.055
- Saeed O, Stein LH, Cavarocchi N, Tatooles AJ, Mustafa A, Jorde UP, Alvarez C, Gluck J, Saunders P, Abrol S, De Anda A Jr, Goldstein DJ, Silvestry S. “Outcomes by Cannulation Methods for Venovenous Extracorporeal Membrane Oxygenation during COVID-19: A Multicenter Retrospective Study.” Artif Organs. 2022 Feb 22
- Wang Z, Paul S, Stein LH, Salemi A, Mitra S “Recent Developments in Blood-Compatible Superhydrophobic Surfaces” Polymers 2022, Volume 14, Issue 6, 1075
- Won, E.J, Stein, L.H., “Commentary: Measure twice, but cut early?” JTCVS Open. May 2021. https://doi.org/10.1016/j.xjon.2021.05.015
- Stein LH, Loumiotis I. “Commentary: Freezing elephants: Survival seems better, when will be sure the spine is safer?” Semin Thorac Cardiovasc Surg. 2021 Jun 1:S1043-0679(21)00223-9. doi: 10.1053/j.semtcvs.2021.04.029.
- Stein, LH. “Commentary: Respect or resect: is a good bicuspid valve any better than a good tissue prosthesis?” Semin Thorac Cardiovasc Surg. 2021 Apr 19;S1043-0679(21)00178-7. doi: 10.1053/j.semtcvs.2021.03.030.
- Stein LH. “Commentary: Maybe that valve is a keeper.” Semin Thorac Cardiovasc Surg. 2021 Feb 17:S1043-0679(21)00069-1. Online ahead of print.
- Leung A, Stein LH. “Commentary: Is combining two high risk too high risk?” J Thorac Cardiovasc Surg. 2020 Dec 3:S0022-5223(20)33206-2.
- Samy S, Stein LH. “Commentary: Proximal aortic dissection repair-when have things gone too far?” J Thorac Cardiovasc Surg. 2020 Jun 26:S0022-5223(20)31774-8
- Stein LH, Elefteriades JA. Commentary: Commentary: Like the children of Lake Wobegon: All aortic cannulation strategies are above average. J Thorac Cardiovasc Surgery, 2020. In press
- Thakral A, Stein L, Shenai M, Gramatikov BI, Thakor, N.V. “Effects of Anodal vs. Cathodal Pacing on The Mechanical Performance of the Isolated Rabbit Heart” Journal of Applied Physiology. 2000 89: 1159-1164.
- Stein, LH, Britton, LW. “Commentary: Mitral repair – where it all comes together?” J Thorac Cardiovasc Surgery. 2020 Mar;159(3):e187.
- Ziegler KR, Stein LH. “Commentary: Sometimes an old dogma needs a new stent.” J Thorac Cardiovasc Surg. 2020 Jan 7. pii: S0022-5223(20)30017-9.
- Stein LH, Samy S. “Commentary: Innovation favors the prepared mind.” J Thorac Cardiovasc Surg. 2019 Oct 3. pii: S0022-5223(19)32383-9.
- Gross DJ, Zangbar B, Muthu N, Chang EH, Badami A, Stein L, Gruessner R, Poston R. “Saving the split: the benefits of VATS thymectomy.” J Thorac Dis. 2019 Apr;11(4):1428-1432.
- Stein LH, Rubinfeld G, Balsam LB, Ursomanno P, DeAnda A. “Too Cold to Clot? Does Intraoperative Hypothermia Contribute to Bleeding Following Aortic Surgery?” Aorta (Stamford).
- Son AY, Stein LH, DeAnda A, Katz SD, Smith D, Reyentovich A, Balsam LB. “Impact of chlorhexidine gluconate intolerance on driveline infection during chronic HeartMate II left ventricular assist device support.” Int J Artif Organs. 2017 Jan
- McGillicuddy EA, Maxfield MW, Salameh B, Stein LH, Ahmad U, Longo WE. “Bleeding diatheses and preoperative screening.” J Surg Educ. 2013 May-Jun;70(3):423-312
- Stein LH, Berger J, Tranquilli M, Elefteriades JA, “Effect of statin drugs on thoracic aortic aneurysms.” Am J Cardiol. 2013 Oct 15;112(8):1240-5.
- Rosenberger LH, Stein LH, Witkiewicz AK, Kennedy EP, Yeo CJ. “Intraductal papillary mucinous neoplasm (IPMN) with extra-pancreatic mucin: a case series and review of the literature.” J Gastrointest Surg. 2012 Apr;16(4):762-70.
- Stein LH, Elefteriades JA. “Can the Occurrence of Gastrointestinal Bleeding in Nonpulsatile Left Ventricular Assist Device Patients Provide Clues for the Reversal of Arteriosclerosis?” Cardiol Clin. 2011 Nov;29(4):641-5.
- Rittenhouse DW, Kennedy EP, Mascaro AA, Brumbaugh JL, Stein LH, Rosenberger LH, Sauter PK, Yeo CJ, Lavu H. “The Novel Triad of Dorsal Agenesis of the Pancreas with Concurrent Pancreatic Ductal Adenocarcinoma and Nonalcoholic Chronic Calcific Pancreatitis: A Case Series and Review of the Literature.” J Gastrointest Surg. 2011 Apr 22.
- Stein LH, Elefteriades JA, “Protecting the Brain During Aortic surgery: An Enduring Debate with Unanswered Questions.” J Cardiothorac Vasc Anesth. 2010 Apr;24(2):316-21.
- Stein LH, Redding KM, Lee JJ, Nolan TJ, Schad GA, Lok JB, Abraham D. “Eosinophils utilize multiple chemokine receptors for chemotaxis to the parasitic nematode Strongyloides stercoralis.” J Innate Immun. 2009 Oct;1(6):618-30
- Stein LH and Silvestry SC "The Use of Intraoperative Doppler Assessment to Guide the Surgical Treatment of Anomalous Right Coronary Arteries" Journal of Cardiac Surgery. 2008 May 14.
- Padigel UM, Stein L, Redding K, Lee JJ, Nolan TJ, Schad GA, Birnbaumer L, Abraham D. “Signaling Through Gαi2 Protein is Required for Recruitment of Neutrophils for Antibody Mediated Elimination of Larval Strongyloides stercoralis in Mice.” J Leukoc Biol. 2007 Apr;81(4):1120-6.
- Marelli DM, Silvestry SC, Zwas D, Mather P, Rubin S, Rodriguez, E, Dempsey AF, Stein LH, Diehl JD, Feldman AM “Modified Inferior Vena Cava Anastomosis to Reduce Tricuspid Valve Regurgitation After Orthotopic Heart Transplantation” Journal of the Texas Heart Institute, 2007;34:555-555.
- Fryer AD, Stein LH, Nie Z, Curtis DE, Evans CE, Hodgson ST, Jose PJ, Belmonte KE, Fitch EF, Jacoby DB, "Neuronal Eotaxin and the Effects of CCR3 Antagonist on Airway Hyperreactivity and M2 Receptor Dysfunction" Journal of Clinical Investigation. 2006. January 4;116(1):228-236.
Books, Monographs, and Chapters:
- Stein L. Choudhary M, Silvestry, S. “The Current Era of Donor Allocation” in Heart Transplantation. Loforte (Ed) Intech. 2018
- Stein L and Silvestry, S. “Proposed Changes in the Heart Organ Allocation System” in Contemporary Heart Transplantation. Bogar and Mountis (Eds) 1st Edition. Springer, 2018.
- Stein, LH, and Elefteriades, JA. “Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms” in Thoraco-Abdominal Aorta Surgical and Anesthetic Management. Coselli, J.S. (Guest Ed.) Chiesa, Roberto; Melissano, Germano; Zangrillo, Alberto (Eds.) 1st Edition. Springer, 2011
- Marelli D, Stein L, Ardehali A, Left ventricular assist devices for acute and chronic heart failure. In, Heart Failure: Device Management – Vol.II. Feldman, A ed. Blackwell Publishers. 2010